Neuromodulation
Neuromodulation Hub: The mission of the Neuromodulation Hub is to facilitate clinical research using non-invasive brain stimulation to investigate neurological and psychiatric conditions across the lifespan. Through the Non-invasive Neuromodulation Laboratories and support from the MnDRIVE Brain Conditions program, we maintain cutting-edge facilities that enable research into novel diagnosis and treatment methods for individuals living with brain conditions. The Hub fosters innovation by supporting pilot studies and early-stage projects, providing the foundation for groundbreaking research in brain stimulation.
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Our Expertise
We facilitate clinical research using non-invasive brain stimulation (NIBS) approaches such as transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to measure and modulate brain activity. We equip investigators with the consultation, training, space, and equipment they need to conduct cutting-edge NIBS research. Find out more at our Non-invasive Neuromodulation Lab (NNL) webpage
How We Engage
Our Team
Christine Conelea, PhD
Associate Professor, Psychiatry and Behavioral Sciences
Director, MIDB Neuromodulation Hub
Kelvin Lim, MD
Professor, Psychiatry and Behavioral Sciences
Director, Non-invasive Neuromodulation Laboratories
Mo Chen, PhD
Technical Consultant to the Non-invasive Neuromodulation Laboratories
Adjunct Associate Professor, Psychiatry and Behavioral Sciences
Mia Kellman
Research Professional 1, Psychiatry and Behavioral Sciences
Alana Lieske
Lab Manager, Psychiatry and Behavioral Sciences
Examples of Our Engagement
CBIT+TMS Study
The CBIT+TMS Study integrates Comprehensive Behavioral Intervention for Tics (CBIT) with Transcranial Magnetic Stimulation (TMS) for participants aged 12–21 who experience tics. This project explores whether pairing behavioral therapy with TMS can improve outcomes for youth with tic disorders.
Hub contributions: IDE Support · Personnel Training · Direct Project Execution
Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior and Neurometabolite Markers of Suicide-Related Cognition in Adolescents
This study investigates how differences in brain signaling and neurochemistry relate to impulsivity, emotion regulation, and suicidal thoughts and behaviors among adolescents aged 13–21. Using MRI, TMS, behavioral tasks, and clinical assessments, the study aims to identify neurobiological markers linked to suicide risk and resilience.
Hub contributions: Consultation · Personnel Training · Direct Project Execution
NExT Study: Neuromodulation and Exposure Therapy for OCD
The NExT Study is a clinical trial for youth and young adults aged 12–21 with Obsessive-Compulsive Disorder (OCD). The study tests whether combining Exposure and Response Prevention (ERP) therapy with Transcranial Magnetic Stimulation (TMS) can enhance treatment effectiveness by modulating brain circuits involved in OCD.
Hub contributions: IDE Support · Personnel Training · Direct Project Execution